This program focuses on doctoral research within Biomedical Sciences, with a specific dissertation example exploring the molecular mechanisms of Amyotrophic Lateral Sclerosis (ALS), particularly the role of misfolded SOD1 protein. Research involves investigating protein interactions, cellular toxicity, and utilizing transcriptomic data to understand disease pathways. The work aims to identify binding partners and pathways associated with SOD1 trimers, comparing them to wild-type SOD1 dimers. Computational and biochemical methods are employed for detailed characterization of identified proteins. The research also considers the application of induced pluripotent stem cells (iPSCs) as disease models and the broader implications of oligomers in ALS research, suggesting potential pathways in the disease's etiology affecting both nerves and muscles.
Graduates of the PhD in Biomedical Sciences program are prepared for careers in research and academia, contributing to advancements in medicine and biology. Specific career outcomes for this dissertation topic include roles in neurodegenerative disease research.
Please refer to the Graduate School and the specific program for detailed admission requirements.
Tuition and fees are subject to change and vary by campus.
The application period for the PhD in Biomedical Sciences opens on June 15th, and the application deadline is December 15th.
Tuition and fees vary by campus and are subject to change. Specific rates for Non-Pennsylvania residents, including international students, differ from Pennsylvania residents. Estimated living costs are not provided.
Graduates are prepared for careers as Researchers, Academic Faculty, and Biomedical Scientists, contributing to advancements in medicine and biology, with specific roles in neurodegenerative disease research.
The program accepts applications for Doctoral degree programs. Prospective students should review the Graduate Degree Bulletin and the J. Jeffrey and Ann Marie Fox Graduate School admissions process for detailed requirements.
Required documents include transcripts, test scores, recommendation letters, and supplemental application materials.