OXFORD BROOKES UNIVERSITY · UNITED KINGDOM
Nigel Groome Studentship: Investigating the role of non-coding RNAs in patient pancreatic neuroendocrine tumour cells, extracellular vesicles and blood samples and their function in cancer development
PhD · Taught in en
At a glance
36 mo
Duration
6.5
IELTS
—
Tuition / yr
en
Language
PhD
Level
- 3 yearsDuration
- UKRI National Minimum Stipend + Fees CoveredBursary
- September 2025 / October 2025Start Date
- Headington CampusLocation
- School of Biological and Medical SciencesSchool
This PhD studentship focuses on understanding the role of non-coding RNAs (ncRNAs), specifically microRNAs (miRNAs), in pancreatic neuroendocrine tumours (PNETs). These molecules are crucial for regulating gene transcription, and their function in PNETs is not well understood. There is a significant clinical need for improved PNET screening, diagnosis, and targeted therapies, especially as the cancer is often diagnosed at a metastatic stage. This project will combine computational analysis with laboratory experiments. The research will identify key miRNAs in PNETs, map their associated biological pathways, and explore their potential as disease biomarkers. The study will involve examining miRNA expression in PNET cell lines derived from patients, as well as in extracellular vesicles from patient blood samples and existing online data. Genomic tools will be employed to investigate the expression of crucial proteins after manipulating miRNA levels in PNET cells. This research aims to contribute valuable insights into the mechanisms driving PNET development and potentially identify new avenues for diagnosis and treatment.
Careers
This PhD equips graduates with advanced research skills and in-depth knowledge in cancer biology and molecular mechanisms. Graduates are well-prepared for careers in scientific research, academia, and the biotechnology and pharmaceutical industries.
- Postdoctoral Researcher
- Research Scientist
- Lecturer/Academic
- Biotechnology roles
- Pharmaceutical roles
Entry requirements
Honours DegreeA first or upper second-class honours degree (or acceptable equivalent qualification) from a UK Higher Education Institution.
IELTS AcademicOverall minimum score of 6.5 to 7.0, with no score below 6.0, issued within the last 2 years.
EU applicants must provide a valid IELTS certificate.
Fees
Tuition (international)University fees and bench fees will be met by the University for the 3 years of the studentship. Visa & associated costs are not funded.
Tuition (home)University fees and bench fees will be met by the University for the 3 years of the studentship.
LivingEstimated annual living costs range from £16,796 to £22,256 for a 52-week year. This includes accommodation, food, transport, and personal expenses.
The studentship covers tuition and bench fees for 3 years. A bursary is provided equivalent to the UKRI national minimum stipend plus fees (current 2024/25 rate: £19,237 p.a.).
How to apply
1. Download Application GuidanceDownload and carefully follow the guideline instructions provided for the Nigel Groome Studentship application.
2. Prepare ApplicationGather all necessary documents and information as outlined in the application guidance.
3. Submit ApplicationSubmit your completed application by the deadline: Friday 17 January 2025, 12 noon.
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